Leukocyte adhesion deficiency type III (LAD III)

Author: V. Dimov, M.D., Allergist/Immunologist and Assistant Professor at University of Chicago
Reviewer: S. Randhawa, M.D., Allergist/Immunologist and Assistant Professor at LSU (Shreveport) Department of Allergy and Immunology

Phagocyte immunodeficiencies (click to enlarge the image):



In leukocyte adhesion deficiency type III, there is a normal expression, but defective activation of β1, β2, and β3 integrins suggesting defect in one or more intracellular signaling molecules.

Published: 08/29/2009
Updated: 08/29/2009