Author: V. Dimov, M.D., Allergist/Immunologist and Assistant Professor at University of Chicago
Reviewer: S. Randhawa, M.D., Allergist/Immunologist and Assistant Professor at LSU (Shreveport) Department of Allergy and Immunology
Cystic Fibrosis
C
CF
Caucasians
Children
CFTR gene mutation
Chronic lung infections
Cirrhosis
Chloride in sweat
Chest physiotherapy
Alpha-1 Antitrypsin Deficiency
Over 95% of cases of pulmonary and hepatic disease are due to to the Pi-ZZ phenotype.
Z means
Zig-zagged A1AT in the endoplasmic reticulum
Interstitial Lung Diseases (ILD)
I
ILD
IPF 30%
Idiopathic
Ineffective CS
There are 4 histology patterns in ILD -- BLUD:
BIP, bronchiolitis with interstitial pneumonia
LIP, lymphocytic interstitial pneumonia
UIP, usual interstitial pneumonia, this is IPF
DIP, desquamative interstitial pneumonia
R
Reticular pattern, more than 25% of lung involved
Resistance to CS
Chronic Obstructive Pulmonary Disease (COPD)
Treatment -- B CAOS:
Bronchodilators
Corticosteroids
Antibiotics and Vaccinations
Oxygen
Smoking cessation
Allergic Bronchopulmonary Aspergillosis (ABPA)
A
ABPA
Asthma
Aspergillus
Created: 02/08/2008
Updated: 02/09/2008
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